Klinische Studien und medizinische Übersichtsartikel

Szyc Ł, Hillen U, Scharlach C, Kauer F, Garbe C. (2019) 'Diagnostic Performance of a Support Vector Machine for Dermatofluoroscopic Melanoma Recognition: The Results of the Retrospective Clinical Study on 214 Pigmented Skin Lesions. Diagnostics.

https://www.ncbi.nlm.nih.gov/pubmed/31450697

Łukasz Szyc, Constantin Scharlach. (2018) 'Die diagnostische Genauigkeit der Melanom-Frühdiagnostik in-vivo mittels Dermatofluoroskopie. Die Ergebnisse einer PMCF-Studie an 214 verdächtigen melanozytären Läsionen.' ePoster Session presented at 28. Deutscher Hautkrebskongress: ADO ePoster

Fink C., Uhlmann L., Hofmann M., Forschner A., Eigentler T., Garbe C., Enk A., Haenssle HA. (2017). 'Patient acceptance and trust in automated computer-assisted diagnosis of melanoma with dermatofluoroscopy.' Journal der Deutschen Dermatologischen Gesellschaft. https://www.ncbi.nlm.nih.gov/pubmed/29927518

A. Forschner, U. Keim, M. Hofmann, I. Spänkuch, D. Lomberg, B. Weide, I. Tampouri, T. Eigentler, C. Fink, C. Garbe1, H. A. Haenssle. (2018) 'Diagnostic accuracy of dermatofluoroscopy in cutaneous melanoma detection: Results of a prospective multicentre clinical study in 476 pigmented lesions' British Journal of Dermatology. https://onlinelibrary.wiley.com/doi/abs/10.1111/bjd.16565

Welzel, J, and E. Sattler (2016) 'Neue Melanomdiagnostik auf der Basis von selektiv angeregter Melaninfluoreszenz mittels stufenweiser Zweiphotonen-Exzitation.” In Nichtinvasive Physikalische Diagnostik in der Dermatologie, pages 119–22, Springer Verlag

Scholz, M., S. Buder, K. Kerl, Re. Dummer, and C. Garbe.(2014) 'New Diagnostic Method for Lesions With Transepidermal Melanocytic Migration (TEM).' JAMA Dermatology 171 (3): 235–41 https://www.ncbi.nlm.nih.gov/pubmed/24760281

Freudenberger S. (2014) Der Informationsgehalt der Melanin-dominierten Fluoreszenz pigmentierter kutanere Läsionen in Paraffin. Aussagen in Relation zum histologischen Befund. Dissertation, Universität Tübingen. https://bibliographie.uni-tuebingen.de/xmlui/handle/10900/58850

Scholz, M., G. Stankovic, C. Scholz, D. Leupold, S. Buder, P. Kohl, R. Eichhorn, M. Stuecker, and K. Hoffmann (2012) 'En Route to a New in Vivo Diagnostic of Malignant Pigmented Melanoma.' Pigment Cell and Melanoma Research 25 (2): 281–83. http://onlinelibrary.wiley.com/doi/10.1111/j.1755-148X.2012.00966.x/pdf

 Leupold, D., M. Scholz, G. Stankovic, J. Reda, S. Buder, R. Eichhorn, G. Wessler, M. Stücker, K. Hoffmann, C. Garbe (2011). 'The Stepwise Two-Photon Excited Melanin Fluorescence Is a Unique Diagnostic Tool for the Detection of Malignant Transformation in Melanocytes.' Pigment Cell and Melanoma Research 24 (3): 438–45. https://www.ncbi.nlm.nih.gov/pubmed/21457482

Patent: LTB Lasertechnik Berlin GmbH. 2008. Ortsaufgelöstes Messverfahren für die Detektion von Melanin in Fluorophorgemischen in einer Festkörperprobe. Erfinder: Matthias Scholz und Dieter Leupold. 08.02.2008. DE. 10 2006 029 809.8.

Leupold, D., Ł. Szyc, M. Schneider, M. Scholz, S. Buder, and H.G. Giering (2017) 'Der universelle Fingerabdruck des Melanoms in der Dermatofluoroskopie.' Poster Session presented at: 25. Jahrestagung Der Arbeitsgemeinschaft Dermatologische Histologie.

Szyc, Ł., D. Leupold, S. Buder, and H.G. Giering (2017) 'Übergang aus der horizontalen in die vertikale Wachstumsphase bei Lentigo Maligna: Charakterisierung mittels Dermatofluoroskopie.' Poster Session presented at: 25. Jahrestagung Der Arbeitsgemeinschaft Dermatologische Histologie.

Szyc, Ł, D. Leupold, G. Stankovic, L. Pfeifer, M. Scholz, S. Buder, H.G. Giering (2017) 'Diagnostik und Verlaufskontrolle verdächtiger pigmentierter Hautläsionen mittels Dermatofluoroskopie' Poster Session presented at: 27. Deutscher Hautkrebskongress: ADO.

Fink, C., and H. A. Haenssle (2016) 'Strategien zur nichtinvasiven Diagnostik des Melanoms.' Hautarzt 67 (7): 519–28. doi:10.1007/s00105-016-3796-0 https://link.springer.com/article/10.1007/s00105-016-3796-0

Leupold, D, G Stankovic, P Riederer, C M Monoranu, Th Müller, and H Giering (2016) 'Increased Risk of Melanoma without Pigmentation Change . Results of Dermatofluoroscopy of Parkinsonians.' Poster Session presented at: 16th World Congress on Cancers of the Ski.

Scholz, M, D Leupold, Ł Szyc, G Stankovic, L Pfeifer, S Buder, and H Giering (2016) 'Follow-up Atypical Melanocytic Lesions with Dermatofluoroscopy : Rapid Malignant Degeneration , Stable State or Repair.' Poster Session presented at: 16th World Congress on Cancers of the Skin

Giering, H, S Buder, G Stankovic, and D Leupold (2016) 'Spitz Tumors and Other Histopathological Pitfalls: Diagnosis with Dermatofluoroscopy.” Poster Session presented at: 16th World Congress on Cancers of the Skin.

Nouri, N, I. Spänkuch, D. Lomberg, I. Tampouri, A. Forschner, and C. Garbe (2016) 'Two-Photon-Excitation Melanin Fluorescence Measurement for Melanoma Detection.' Poster Session presented at: 16th World Congress on Cancers of the Skin

Fink C, Hofmann M, Jagoda A, et al. Study protocol for a prospective, non-controlled, multicentre clinical study to evaluate the diagnostic accuracy of a stepwise two-photon excited melanin fluorescence in pigmented lesions suspicious for melanoma (FLIMMA study). BMJ Open 2016;6: e012730. doi:10.1136/ bmjopen-2016-012730

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5168683/

Spänkuch, I., A. Forschner, and C. Garbe (2015) In Vivo Melanin Fluorescence Spectra in Typical Cases of Melanoma and Melanocytic Nevi.' Poster Session presented at: 11th EADO Congress and 8th World Meeting of Interdisciplinary Melanoma/Skin Centers.

Buder, S., D. Leupold, G. Stankovic, C. Zesch, L. Pfeifer, M. Scholz, G. Metzler, and J. Bauer (2015) 'Erweiterte Diagnostik Bei Atypischen Spitz Tumoren.' Poster Session presented at: 23. Jahrestagung der Arbeitsgemeinschaft Dermatologische Histologie (ADH).

Buder, S., D. Leupold, G. Stankovic, C. Zesch, L. Pfeifer, M. Scholz, G. Metzler, and J. Bauer (2014) “Erweiterte Diagnostik Bei Atypischen Spitz Tumoren.” Poster Session presented at: 22. Jahrestagung der Arbeitsgemeinschaft Dermatologische Histologie (ADH).

Buder, S., R. Eichhorn, J. Bauer, M. Scholz, G. Stankovic, L. Pfeifer, C. Zesch, and D. Leupold (2014) 'Diagnostics of Spitz Tumors and Congenital Nevi: New Access via Melanosome Fluorescence.' Poster Session presented at: 12. European Society for Pediatric Dermatology Congress.

Leupold, D., M. Scholz, G. Stankovic, L. Pfeifer, H.G. Giering, S. Buder, J. Bauer, R. Dummer, and C. Garbe (2014) 'Uniform Spectral Fingerprint of the Different Melanoma Subtypes: Diagnostic Utility and Mechanistic Implications.' Poster Session presented at: 11th International Congress of the Society for Melanoma Research.

Eichhorn, R, G Wessler, G Stankovic, M Scholz, L Pfeifer, S Buder, and D Leupold (2013) 'Melanin Fluorescence Based in Vivo-Follow-up Study of Dysplastic Nevi. Relations to Models of Nevogenesis.' Poster Session presented at: World Congress of Melanoma, Hamburg.

Pfeifer, L, U. Zabarylo, G. Stankovic, N. Bensmann, and O. Minet (2013) 'Vitality of the MeWo Melanoma Cell Line during Intense Nanosecond-Pulsed NIR Laser Radiation.' Laser Physics Letters 11 (1): 15601. http://iopscience.iop.org/article/10.1088/1612-2011/11/1/015601

Buder, S, P. Kohl, G. Stankovic, J. Reda, D. Leupold, M. Scholz, G. Wessler, R. Eichhorn, M. Stücker, K. Hoffmann, S. Freudenberger, J. Bauer, and C. Garbe (2011) 'Früherkennung und Charakterisierung pigmentierter Melanome.' Poster Session presented at: JDDG-Tagung Dresden

R. Eichhorn, G. Wessler, M. Scholz, D. Leupold, G. Stankovic, S. Buder, M.Stücker, K. Hoffmann, Early diagnosis of melanotic melanoma based on laser-induced
melanin fluorescence, J. Biomed. Opt., Vol. 14, 034033 (2009)

Eichhorn, R, G Wessler, S Buder, K Hoffmann, M Stücker, J Reda, G Stankovic, D Leupold, and M Scholz (2009) 'A New , Melanin Fluorescence-Based Method for Early Detection of Melanotic Melanoma.' Poster Session presented at: 3rd World Meeting of Interdisciplinary Melanoma/ Skin Cancer Centers.

Eichhorn, R., G. Wessler, S. Buder, D. Leupold, G. Stankovic, J. Reda, and M. Scholz. (2009) 'Eine Neue Früherkennungsmethode Für Das Maligne Melanom' Die Haut 5 (XX).

Eichhorn, R., G.Wessler, M. Scholz, D. Leupold, G. Stankovic, S. Buder, M. Stücker, and K. Hoffmann. (2009) 'Early Diagnosis of Melanotic Melanoma Based on Laser-Induced Melanin Fluorescence.' Journal of Biomedical Optics 14 (3): 34033.

Scholz, M., G. Stankovic, G. Seewald, and D. Leupold (2007) 'Uncovering of melanin fluorescence in human skin tissue.' Proc. SPIE 6633, 21-26

https://www.spiedigitallibrary.org/conference-proceedings-of-spie/6633/1/Uncovering-of-melanin-fluorescence-in-human-skin-tissue/10.1117/12.728272.short

Hoffmann, K., N.S. Tomi, M. Stücker, F. Bechara, M. Scholz, G. Stankovic, R. Eichhorn, and D. Leupold (2007) Melanin-Based Early Diagnosis of Melanotic Melanoma: Fluorescence Fingerprint Uncovered by Nanosecond-Laser Excitation.' Poster Session presented at: 21th World Congress of Dermatology.

Hoffmann, K., N. Tomi, F. Bechara, M. Scholz, R. Eichhorn, and D. Leupold (2007) Early Diagnosis of Melanocytic Melanoma Based on Melanin Fluorescence.' Poster Session presented at: 21th World Congress of Dermatology

Schneider, M., K. Teuchner, and D. Leupold (2005) 'Two-photon fluorescence of ocular melanomas. Studies on a new diagnostic method' Ophthalmologe 102: 703-7.

https://www.ncbi.nlm.nih.gov/pubmed/15672247

Teuchner, K., S. Mueller, W. Freyer, D. Leupold, P. Altmeyer, M. Stücker, and P. Hoffmann (2003) 'Femtosecond two-photon excited fluorescence of melanin.' Poc. SPIE 4797; 211-219 https://www.spiedigitallibrary.org/conference-proceedings-of-spie/4797/1/Femtosecond-two-photon-excited-fluorescence-of-melanin/10.1117/12.453312.short

Hoffmann, K., M. Stucker, P. Altmeyer, K. Teuchner, and D. Leupold (2001) 'Selective femtosecond pulse-excitation of melanin fluorescence in tissue.' J Invest Dermatol 116: 629-30 https://core.ac.uk/download/pdf/82703789.pdf

Teuchner, K., J. Ehlert, and W. Freyer (2000) 'Fluorescence studies of melanin by stepwise two-photon femtosecond laser excitation' J. of Fluorescence20: 275-81. https://link.springer.com/article/10.1023/A:1009453228102